Publications

2023

Wei-Ting Liu, Han-Tang Wang, Yi-Hsuan Yeh, and Tak-Wah Wong.* An Update on Recent Advances of Photodynamic Therapy for Primary Cutaneous Lymphomas. Pharmaceutics. Accepted April 22,2023. Impact factor 6.525, Journal Rank: JCR - Q1 (Pharmacology & Pharmacy)

Figure. Photodynamic therapy as an adjunctive treatment in primary cutaneous lymphomas in 2 patients. A 63-year-old woman with stage IIA mycosis fungoides who received oral retinoid acid and UVB phototherapy except for the face due to the fear of skin darkening. (a) There are a few well-demarcated scaly erythematous patches on the forehead that responded poorly to topical treatments. (b) 5-aminolevulinic acid (ALA)-PDT consisted of 50 J/cm2 visible light (MediLED PDT, Mediland, Taoyuan City, Taiwan) irradiance after occlusion of 5-aminolevulinic acid (Ameluz, Biofrontera AG, Leverkusen, Germany) for 3 h given every other week for 3 sessions, and strong fluorescence was shown under Wood’s light examination. (c) After 3 treatment sessions, the erythematous scaly patches over the forehead improved greatly, although a histological exam over the right forehead lesion revealed residual atypical lymphocytes. (d) A 56-year-old woman with mycosis fungoides and lymphomatoid papulosis developed new crops of papules over the V-chest despite being under treatments with twice-weekly PUVA phototherapy and weekly 10 mg oral methotrexate. (e) Vivid coral-red fluorescence was detected under Wood’s lamp illumination after occlusion with ALA for 3 h. (f) Significant improvement was achieved after a single treatment with 100 J/cm2 visible light irradiation at 2-week follow-up.

2022

Tzu-Kun Lo, Yu-Chen Chen, Wei-Ting Liu, Tak-Wah Wong.* Successful treatment of giant Bowen's disease with photodynamic therapy and subsequent imiquimod in a case with chronic arsenic exposure. Photodiagnosis and Photodynamic Therapy. Available online 20 September 2022, 103128. https://doi.org/10.1016/j.pdpdt.2022.103128

Figure: A 74-year-old female with chronic arsenic intoxication presented with 2 giant Bowen's disease lesions on her back for 3 years, were successfully treated with photodynamic therapy (PDT), followed by imiquimod occlusion. A. The upper lesion was 10.5 cm x 3.5 cm, the lower tumor was 12 cm x 3 cm in diameters, respectively. Some smaller lesions were noted around the main tumors. The tumor was painful that make her hard to lie flat while sleeping. B. Vivid coral red fluorescence of protoporphyrin IX (PpIX) was detected under Wood's lamp after 3-hour occlusion with aminoleyulinic acid represented the well absorption and biosynthesis of PpIX in tumor cells. C. One week after PDT and biweekly 5% imiquimod overnight occlusion, the tumors were eroded, and tumors on the margins cleared (arrows). Patient reported that she could sleep well after the treatment. D. No tumor recurred at the 12-month follow-up. Bar = 5 cm.

Shu-Hao Chang, Pei-Ying Lin, Tzai-Kun Wu, Chien-Sheng Hsu, Shi-Wei Huang, Zheng-Yi Li, Kuang-Ting Liu, Jun-Kai Kao, Yi-Ju Chen, Tak-Wah Wong. Chun-Ying Wu, Jeng-Jer Shieh. Imiquimod-induced ROS production disrupts the balance of mitochondrial dynamics and increases mitophagy in skin cancer cells. J Dermatol Sci 2022 Jun;98(3): 152-162. https://doi.org/10.1016/j.jdermsci.2022.08.006. Impact factor: 5.408 9/68 (Dermatology)

Figure: IMQ induced lysosomal damage and dysfunction in skin cancer cells. (A) IMQ decreased the stability of lysosomes in BCC cells. (B) IMQ enhanced galectin-3 puncta formation in A375 cells. (C) IMQ triggered lysosomal CTSD release into the cytosol in BCC and A375 cells. (D) IMQ increased lysosomal pH in BCC and A375 cells. (E) IMQ decreased CTSD activity in BCC cells. BCC and A375 cells were treated with 50 μg/ml IMQ for 24 h or at different time points or Leu-Leu (4 mM) for 24 h. (A) The stability of lysosomes was examined by AO staining. Scale bars, 20 µm. (B) Lysosomal leakage was determined by galectin-3 staining by immunocytochemistry. Scale bars, 20 µm. (C) Representative images show immunofluorescence staining of LAMP1 (green fluorescence) and CTSD (red fluorescence) in BCC and A375 cells. The CTSD subcellular translocation was detected by confocal microscopy. Scale bars, 20 µm. (D) Lysosomal pH was measured by LysoSensor staining. (E) CTSD activity in BCC cells was measured by fluorometric CTSD activity assay kits and an ELISA reader. The data are expressed as the mean± SEM of at least three independent experiments (*** p < 0.001).

Chrong-Reen Wang, Tak-Wah Wong*, Sheng-Min Hsu. Extended-release tofacitinib for refractory Behçet disease: A case report. Medicine (Baltimore). 2022 Apr 15;101(15):e29189.

Figure. A. Multiple irregular-shaped ulcers over the lips (arrows). B. Whitish patches over the tongue with the isolation of Candida glabrata. Irregular-shaped ulcers over the lip and tongue (arrows).

Astrid M van Huizen ... Tak-Wah Wong*... et al. An international eDelphi study to reach consensus on the methotrexate dosing regimen in psoriasis. JAMA Dermatology, 2022 Mar 30. doi: 10.1001/jamadermatol.2022.0434. Impact factor 10.282. Ranking 2/69 in Dermatology.

Jia-Horung Hung, Zhao-Xiang Wang, Yuan-Hsin Lo, Chaw-Ning Lee, Yun Chang, Rita Yuchiao Chang, Chien-Chun Huang, Tak-Wah Wong.* Rose Bengal-Mediated Photodynamic Therapy to Inhibit Candida albicans. JoVE accepted 22.02.17. Impact factor 1.4.

Figure : The time-dependent study of Rose bengal entering C. albicans. Bright-field (A–D) and fluorescence images (E–H) of the C. albicans after 0–30 min co-cultured with 0.2% Rose bengal (RB). (A) and (E) Control without RB co-cultured. (B) and (F) The cells were immediately stained with 0.2% RB. (C) and (G) After 15 min of culture, most cells showed red fluorescence, indicating RB inside the cells. (D) and (H) Stronger fluorescence of the RB was noted with a 30 min incubation. Scale bar = 50 μm.

Jeu-Ming P. Yuann, Shwu-Yuan Lee, Sin He, Tak-Wah Wong, Meei-Ju Yang, Chien-Wei Cheng, Shiuh-Tsuen Huang* and Ji-Yuan Liang.* The effects of free radicals from doxycycline hyclate and minocycline hydrochloride under blue light irradiation on the deactivation of Staphylococcus aureus, including a methicillin-resistant strain. Journal of Photochemistry & Photobiology, B: Biology (21.11.24, accepted) Volume 226, January 2022, 112370. https://doi.org/10.1016/j.jphotobiol.2021.112370. Impact factor: 6.25 Q1 11%.

Neil Adrian P. Ondevilla, Tak-Wah Wong, Nan-Yao Lee, Hsien-Chang Chang.* An AC electrokinetics-based electrochemical aptasensor for the rapid detection of microRNA-155. Biosensors and Bioelectronics (Accepted, 21.11) Volume 199, 1 March 2022, 113847 Impact Factor: 10.618, ranking: 3/83 in Chemistry, Analytical. https://doi.org/10.1016/j.bios.2021.113847

Scheme 1. Surface modification protocol on the surface of the gold electrode. (i) Immobilization of 5′-thiolated anti-miR-155 aptamer for 30 min (Apt/Au); (ii) surface blocking using mercaptohexanoic acid (MCH) for 15 min (MCH/Apt/Au); (iii) miR-155 target hybridization (miR/MCH/Apt/Au). Target hybridization using ACEO was compared with conventional target incubation method for 1 h.

Chaw-Ning Lee, Tzu-Ying Chen, Tak-Wah Wong.* The Immunogenetics of Photodermatoses. Chapter 14 in book “Immunogenetics of dermatologic diseases”, edit by Nima Rezaei. Published by Springer.

Figure. Left: The age of idiopathic photodermatoses in a lifetime. Right: Clinical pictures of polymorphic light eruption. a PMLE lesions presented as plaques; b papules; c insect bite-like, and d papulovesicles.

Chaw-Ning Lee, Tak-Wah Wong.* Chapter "The Immunogenetic Aspects of Photodynamic Therapy" in Adv Exp Med Biol, Vol. 1367, Nima Rezaei and Fateme Rajabi (Eds)_ The Immunogenetics of Dermatologic Diseases, 978-3-030-92615-1, 472236_1_En, (Chapter 18) Chapter DOI 10.1007/978-3-030-92616-8_18.

Fig. a, b A 74-year-old woman with a large pigmented basal cell carcinoma on the forehead treated with ALA-PDT after debulking the main tumor. c Note that minimal scar after wound healing. The patient was clinically free of tumor at a three-year follow-up

2021

Ping-Chen Hou, Chaw-Ning Lee, Tak-Wah Wong, Tzu‐Chien Hsu, Cheng-Lin Wu, Julia Yu-Yun Lee. Clinicopathological study of perianal Paget disease: a single center-based cohort study and literature review. Archives of Pathology & Laboratory Medicine. The Journal of Dermatology (Submitted 21.07).

Jia-Horung Hung, Chaw-Ning Lee, Huai-Wen Hsu, I-Son Ng, Chi-Jung Wu, Chun-Keung Yu, Nan-Yao Lee, Yun Chang and Tak-Wah Wong.* Recent advances in photodynamic therapy against fungal keratitis. Pharmaceutics. Accepted. Impact factor 6.321

Figure. Schematic illustration of antimicrobial photodynamic therapy mechanism for fungal keratitis. The ground-state photosensitizer (PS) absorbs photons and is excited to the first short-lived excited singlet state and either returns to the ground state or undergoes intersystem crossing to a long-lived triplet state. The triplet state PS exerts downstream function via a type I or type II photosensitization process. For type I reaction, charge is transferred from the excited PS to oxygen (O2), and therefore leading to the formation of hydrogen peroxide (H2O2), hydroxyl radical (HO·), and superoxide anion (O2−·). For type II reaction, the triplet PS undergoes energy exchange with triplet ground state oxygen, leading to the formation of singlet oxygen 1O2. Type I and type II reactions can occur at the same time during irradiation. Nevertheless, type II reaction is mainly involved in antimicrobial photodynamic action. The reaction depends most importantly on PS used and the concentration of O2 in aPDT.

Wei-Ting Liu, Chaw-Ning Lee, Yin-Yu Ho, Hsiang-Ying Lu, Chia-Jui Yen,* Tak-Wah Wong.* Successful treatment of disseminated cutaneous lesions of classic type Kaposi sarcoma with low dose peginterferon alfa-2a: A case report. Derm Sinica. Accepted.

Jieh-Neng Wang,* Chung-Dann Kan, Shao-Hsien Lin, MS1, Ke Ji Chang, Stephanie Tsao, Tak-Wah Wong.* Potential of autologous progenitor cells and decellularized porcine artery matrix in construction of tissue-engineered vascular grafts. Organogenesis 2021 Oct 2;17(3-4):72-84. doi: 10.1080/15476278.2021.1963603.

Pei-Lin Shao, Jiunn-Der Liao*, Shun-Cheng Wu, Yu-Hsing Chen, Tak-Wah Wong. Microplasma treatment versus negative pressure therapy for promoting wound healing in diabetic mice. Int. J. Mol. Sci. 2021, 22(19), 10266; https://doi.org/10.3390/ijms221910266

Figure. Schematic representation of the animal testing model with six study groups: (1) NP, (2) Control (Ctrl), (3) MP14, (4) GF14, (5) MP28, and (6) GF28. The operation sequences for MP treatment and negative NP therapy in mice are also illustrated.

Chao‐Chun Yang, Chin‐Han Wu, Tak‐Wah Wong, Feng‐Jie Lai, Kai‐Che Wei, Tzu‐Kai Lin, Chrang‐Shi Lin, Juemin Zhao, Leihong Xiang, Chao‐Hsing Kao, Ying‐Jan Wang, Cheng‐Che Eric Lan, Hamm‐Ming Sheu. Effects of Solanum undatum extract (SR‐T100) on photocarcinogenesis and photoaging of actinic keratosis. J of Dermatol First published: 17 January 2021 https://doi.org/10.1111/1346-8138.15703

Figure. Summary of the therapeutic effect of Solanum undatum extract (SR-T100) on cutaneous photocarcinogenesis (CPC) and cutaneous photoaging (CPA). Chronic ultraviolet (UV) exposure resulted in CPC, including actinic keratosis (AK), and CPA (1). Photocarcinogenesis was characterized by upregulation of mutant p53 and SOX2, as well as downregulation of NOTCH1 in the epidermis. Photoaging was characterized by the presence of solar elastosis in the dermis and downregulation of lamin B1 in the epidermis. The therapeutic effect of SR-T100 gel was demonstrated on AK lesions by reversing the dysregulation of the above biomarkers and inducing the neogenesis of elastic fibers (2).

Shu-Hao Chang, Chun-Ying Wu, Kai-Cheng Chuang, Shi-Wei Huang, Zheng-Yi Li,Sin-Ting Wang, Zi-Lun Lai, Cheng-Chung Chang, Yi-Ju Chen, Jun-Kai Kao, Tak-Wah Wong, Jeng-Jer Shieh. Imiquimod accelerated antitumor response by targeting lysosome adaption in skin cancer cells. Journal of Investigative Dermatology. 2021 Sep. 141(9):2219-2228.e8 doi: 10.1016/j.jid.2021.01.034.

Wei-Peng Li*, Chia-Jui Yen, Bo-Sheng Wu, and Tak-Wah Wong.* Recent Advances in Photodynamic Therapy for Deep-Seated Tumors with The Aid of Nanomedicine. Biomedicines. Biomedicines 2021, 9(1), 69; https://doi.org/10.3390/biomedicines9010069

Figure. The principle of photodynamic reaction and its basic limitations applied in deep-seated tumor treatment. PS: Photosensitizer, TME: Tumor microenvironment.

Ming-Hsien Lin, Julia Yu-Yun Lee, Shin-Chen Pan, and Tak-Wah Wong.* Enhancing wound healing in recalcitrant leg ulcers with aminolevulinic acid-mediated antimicrobial photodynamic therapy. Photodiagnosis and Photodynamic Therapy. Volume 33, March 2021, 102149. https://doi.org/10.1016/j.pdpdt.2020.102149

Figure. APDT was applied to the lower ulcer, which healed around 30 % on Day 11 and healed completely by one month. The upper ulcer, which received a sham treatment (red light irradiation without ALA application) did not heal by Day 46. Then it was treated with APDT on this day. The ulcer healed in a month.

Tak-Wah Wong,* Chao-Chun Yang, Chao-Kai Hsu, Cheng-Han Liu, JuliaYu-Yun Lee.* Transplantation of Autologous Single Hair Units Heals Chronic Wounds in Autosomal Recessive Dystrophic Epidermolysis Bullosa: A Proof-of-Concept Study. Journal of Tissue Viability. Volume 30, Issue 1, February 2021, Pages 36-41. https://doi.org/10.1016/j.jtv.2020.11.002

Figure. A middle-aged woman with intermediate autosomal recessive dystrophic epidermolysis bullosa. To heal the chronic ulcers, single hair follicular units are extracted by a 1-mm punch from her scalp and grafted onto her chronic wounds. Most treated ulcers heal in a month with sustained effects, probably by regaining some functional anchoring fibrils derived from the hair follicles (positive type VII collagen expression demonstrated in the scalp follicle and the healed ulcer). This procedure uses the patient's own hair follicles without laboratory manipulation. Thus, it is a simple and safe procedure, which may provide an innovative solution for non-healing ulcers in such patients.

2020

Ming-Hsien Lin, Julia Yu-Yun Lee, Shin-Chen Pan, and Tak-Wah Wong.* Enhancing wound healing in recalcitrant leg ulcers with aminolevulinic acid-mediated antimicrobial photodynamic therapy. Photodiagnosis and Photodynamic Therapy. In press. https://doi.org/10.1016/j.pdpdt.2020.102149

Chaw-Ning Lee, Rosie Hsu, Hsuan Chen, and Tak-Wah Wong.* Daylight Photodynamic Therapy: An Update. Molecules. 2020, 25(21), 5195; https://doi.org/10.3390/molecules2521519

林淳鈺、黃子綾、林宏謙、彭賢禮、王德華*。與醫美醫師有約：談兩岸醫美發展現況。台灣醫界雜誌2020 Vol63, 4.

Wan-Ting Chia, Yen-Chin Liu,* Tak-Wah Wong.* Optimize general anesthesia for a dystrophic epidermolysis bullosa patient that cannot be intubated. Asian Journal of Anesthesiology 1-4, 2020. *Corresponding author. 10.6859/aja.202007/PP.0004

2019

Tak-Wah Wong,* Chung-Dann Kan, Wen-Tai Chiu, Kin Lam Fok, Ye Chun Ruan, Xiaohua Jiang, Junjiang Chen, Chiu-Ching Kao, I-Yu Chen, Hui-Chun Lin, Chia-Hsuan Chou, Chou-Wen Lin, Chun-Keung Yu, Stephanie Tsao, Yi-Ping Lee, Hsiao Chang Chan and Jieh-Neng Wang. Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children. J. Clin. Med. 2019, 8(7), 1028. https://doi.org/10.3390/jcm8071028 Impact factor 5.688 (2018), Ranking: 15/160 (Medicine, General & Internal). In printed edition of the special issue published in MDPI, “New technologies for the treatment of coronary and structural heart diseases” p65-86, edited by Alberto Polimeni.

Tak-Wah Wong*, Shu-Zhen Liao, Wen-Chien Ko, Chi-Jung Wu, Shin Bei Wu, Yin-Ching Chuang and I-Hsiu Huang*. Indocyanine Green—Mediated Photodynamic Therapy Reduces Methicillin-Resistant Staphylococcus aureus Drug Resistance. J Clinic Med. 2019 Mar 25;8(3). *Corresponding author. Impact factor 5.688 (2018), Ranking: 15/154 (Medicine, general & internal). https://doi.org/10.3390/jcm8030411

Wen-Tai Chiu, Thi-Tuong Vi Tran, Shin-Chen Pan, Ho-Kai Huang, Ying-Chi Chen, and Tak-Wah Wong*. Cystic Fibrosis Transmembrane Conductance Regulator: A Possible New Target for Photodynamic Therapy Enhances Wound Healing. Advances in Wound Care. 2 Apr 2019 https://doi.org/10.1089/wound.2018.0927. Impact factor: 3.714 (2018), Ranking 11/66 (Dermatology).

Chein-Hong Lin, Po-Yuan Chiu, Yuan-Yu Hsueh, Shyh-Jou Shieh, Chia-Ching Wu, Tak-Wah Wong, Cheng-Ming Chuong, Michael W Hughes. Regeneration of rete ridges in Lanyu pig (Sus scrofa): Insights for human skin wound healing. Experimental Dermatology. 2019 Apr;28(4):472-479 Impact Factor: 2.868. 19/66 (DERMATOLOGY).

Hsi Yen, Hsing-Jou Su, Thi Tuong Vi-Tran, Pei-Lun Kuo, Tak-Wah Wong*. Childhood and adolescent psoriasis in Taiwan: a retrospective analysis from a single medical center. Dermat Sinica. Accepted, *Corresponding author. Impact factor 0.808 (2018), Ranking: 61/66 (Dermatology)

2018

Tsen-Fang Tsai, Ji-Chen Ho, Yi-Ju Chen, Pa-Fan Hsiao, Woan-Ruoh Lee, Ching-Chi Chig, Cheng-Che Lan, Rosaline Chung-Yee Hui, Yang-Chih Lin, Kuo-Chia Yang, Tak-Wah Wong, Hamm-Ming Sheu, Hsiu-Cheng Hsu, Gong-YauChu, Yu-Huei Huang. Health-related quality of life among patients with moderate-to-severe plaque psoriasis in Taiwan. Dermatologica Sinica 2018 Dec. 36 (4), 190-195. Impact factor 1.050 (2017), Ranking: 61/63 (Dermatology). https://doi.org/10.1016/j.dsi.2018.06.006

Yi Liao,* Hung-Chi Chang, Feng-Xia Liang, Pei-Jung Chung, Yuan Wei, Tuan-Phi Nguyen, Ge Zhou, Sheeva Talebian, Lewis C. Krey, Fang-Ming Deng, Tak-Wah Wong, Javier U. Chicote, James A. Grifo, David L. Keefe, Ellen Shapiro, Herbert Lepor, Xue-Ru Wu, Robert DeSalle, Antonio Garcia-Espana A, Sang Yong Kim, and Tung-Tien Sun*. Uroplakins play conserved roles in egg fertilization and acquired additional urothelial functions during mammalian divergence. Mol Biol Cell. 2018 Oct 10:mbcE18080496. doi: 10.1091/mbc.E18-08-0496. Impact factor 3.512 (2017), Ranking 88/190 (Cell Biology).

Shiuh-Tsuen Huang, Chun-Yi Wu, Nan‐Yao Lee, Chien-Wei Cheng, Meei-Ju Yang, Yi-An Hung, Tak-Wah Wong*, Ji-Yuan Liang*. Effects of 462 nm Light-Emitting Diode on the Inactivation of Escherichia coli and a Multi-Drug-Resistant by Tetracycline Photoreaction. J. Clin. Med. 2018, 7(9), 278; https://doi.org/10.3390/jcm7090278 *Corresponding author. Impact factor 5.583 (2017), Ranking: 15/154 (Medicine, general & internal)

Meei-Ju Yang, Yi-An Hung, Tak-Wah Wong, Nan‐Yao Lee, Jeu-Ming P Yuann, Shiuh-Tsuen Huang, Chun-Yi Wu, Iou-Zen Chen, Ji-Yuan Liang. Effects of Blue-light-induced Free Radical Formation from Catechin Hydrate on the Inactivation of Acinetobacter baumannii including a Carbapenem Resistant Strain. Molecules. 2018 Jul 4;23(7). pii: E1631. doi: 10.3390/molecules23071631. Impact Factor: 3.098 (2018), Ranking: 133/292 (Biochemistry and Molecular Biology); 68/170 (Chemistry, multidisciplinary).

Szu-Han Chen; Tak-Wah Wong; Chou-Hwei Lee; Chung-Lin Chen; Li-Wha Wu; Shin-Chen Pan. Predominance of CD14+ Cells in Burn Blister Fluids. Annals of Plastic Surgery. 80(2S):S70–S74, FEB 2018. Impact factor 1.596. JCR Ranking 2016:108/197 (SURGERY).

Chao-Chun Yang, Tak-Wah Wong, Chih-Hung Lee, Chien-Hui Hong, Chung-Hsing Chang, Feng-Jie Lai, Shang-Hung Lin, Ching-Chi Chi, Tzu-Kai Lin, Hsi Yen, Chin-Han Wu, Hamm-Ming Sheu, Cheng-Che E. Lan. Efficacy and safety of topical SR-T100 gel in treating actinic keratosis in Taiwan: A Phase III randomized double-blind vehicle-controlled parallel trial. https://doi.org/10.1016/j.jdermsci.2018.02.015. Journal of Dermatological Science. 2018 Jun;90(3):295-302. Impact factor 3.73 Racking: 7/63 (Dermatology).

Chaw-Ning Lee, Chun-Cheng Huang, I-Chun Lin, Julia Yu-Yun Lee, Chun-Yen Ou, Tak-Wah Wong.* Recalcitrant lip verrucous carcinoma successfully treated with acitretin after CO2 ablation. JAAD Case Reports. Accepted, *corresponding author. JAAD Case Rep. 2018 Jun 12;4(6):576-578. doi: 10.1016/j.jdcr.2018.02.002. eCollection 2018 Jul.

Tak-Wah Wong*, Michael Hughes, and Szu-Han Wang. Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient? J Tissue Viability. doi: 10.1016/j.jtv.2018.01.001. 2018 May;27(2):114-116. Impact factor: 1.263 Ranking: 50/116 (Nursing).

Tak-Wah Wong*, En-Chi Wu, Wen-Chien Ko, Ching-Chi Lee, Lien-I Hor, I-Hsiu Huang. Photodynamic inactivation of methicillin-resistant Staphylococcus aureus by indocyanine green and near infrared light. Dermatol Sinica. 2018 March;36 (1):8-15. https://doi.org/10.1016/j.dsi.2017.08.003. *Corresponding author. Impact factor 1.050 (2017), Ranking61/63 (Dermatology).

2017

Tak-Wah Wong, Chien-Wei Cheng, Zong-Jhe Hsieh, Ji-Yuan Liang.* Effects of Blue or Violet Light on Inactivation of Staphylococcus aureus by Riboflavin 5’-phosphate Photolysis. J Photochem Photobiol B. 2017 Aug;173:672-680. Impact factor: 3.165, 125/293 (Biochemistry & Molecular Biology) https://doi.org/10.1016/j.jphotobiol.2017.07.009.

Wei-Peng Li, Chia-Hao Su, Sheng-Jung Wang, Fu-Ju Tsai, Chun-Ting Chang, Min-Chiao Liao, Chun-Chieh Yu, Thi-Tuong Vi Tran, Chaw-Ning Lee, Wen-Tai Chiu, Tak-Wah Wong*, and Chen-Sheng Yeh*. CO2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids. ACS Nano. 2017 Jun 27;11(6):5826-5835. *Corresponding author, 13.942. Supported by MOST103-2314-B-006-024. https://doi.org/10.1021/acsnano.7b01442

Tsen-Fang Tsai, Yun-Ting Chang, Chih-Hung Lee, Yu-Huei Huang, Ching-Chi Chi, Tak-Wah Wong, Chih-Hsun Yang, Li-Fang Wang. Taiwanese Dermatological Association consensus statement on management of psoriasis. Dermatol Sinica. 2017, June;35(2), 66-77. Impact factor 1.050 (2017), Ranking: 61/63 (Dermatology).

鄭百珊、謝馥年、林栗伃、陳文杰、紀景琪、藍政哲、李志宏、林子凱、賴豐傑、楊朝鈞、王德華 (Tak-Wah Wong)、許漢銘.日光性角化症-診斷與治療之新概念 Actinic keratosis: new concepts on diagnosis and treatments. Taiwan Medical Journal台灣醫界 (2017, 60 (1): 9-13.

2016

Pei-Lin Shao; Jiunn-Der Liao; Tak-Wah Wong; Yi-Cheng Wang; Steve Leu; Hon-Kan Yip. Enhancement of Wound Healing by Non-Thermal N₂/Ar Micro-Plasma Exposure in Mice with Fractional-CO₂-Laser-Induced Wounds. PLoS One. 2016 Jun 1;11(6):e0156699. Impact factor: 2.806, Ranking: 15/64 (Multidisciplinary Sciences).

Lee CN, Pan SC, Lee JY, Wong TW.* Successful treatment of cutaneous squamous cell carcinoma with intralesional cryosurgery: Case report. Medicine (Baltimore). 2016 Sep;95(39):e4991. *Corresponding author. Impact factor: 1.804, Ranking: 57/155 (Medicine, General and Internal).

Tzu-Chien Hsu, Cheng-Han Liu, Chao-Kai Hsu, Tak-Wah Wong, Julia Yu-Yun Lee. Pigmented hidroacanthoma simplex of the scalp mimicking clonal seborrheic keratosis. Dermatologica Sinica. 2016 Mar; 34(1): 64-65 Impact factor 0.54, Ranking: 61/63 (Dermatology).

2015

Hsi Yen, Shin-Chen Pan, Chien-Hun Huang, and Tak-Wah Wong.* Complete remission of a periorbital dermatofibrosarcoma protuberans with adjuvant imatinib mesylate in a child. J Am Acad Dermatol Case Reports 2015 Jul; 1(4): 172–174. *Corresponding author.

T. Takeichi, Chao-Kai Hsu, Hsing-San Yang, Hung-Yu Chen, Tak-Wah Wong, Wei-Lun Tsai, Sheau-Chiou

　　Chao, Julia Yu-Yun Lee, M. Akiyama, M.A. Simpson, J.A. McGrath. Progressive hyperpigmentation due to 　　　　　　　
　　an inborn error of vitamin B12 metabolism. British Journal of Dermatology 2015 Apr;172(4):1111-5. 　　Impact factor 4.71, Ranking 5/63 (Dermatology).

Yen-Chen Huang, Chin-Te Huang, Chieh Hu, Tak-Wah Wong.* Portable ultraviolet light A1 light source to treat hypertrophic scar. Dermatolgica Sinica March 2015 Volume 33, Issue 1, Pages 11–15. *Corresponding author. Impact factor 0.54, Ranking: 61/63 (Dermatology).

光動力治療創新實驗室 Photodynamic Innovative Laboratory

Publications

2022

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光動力治療創新實驗室
Photodynamic Innovative Laboratory